RT Journal Article
T1 Moderate Physical Activity Generates Changes in Retina and Choroid in Low-Fit Adults
A1 López Cuenca, Inés
A1 Hoz Montañana, María Rosa De
A1 Elvira Hurtado, María Lorena
A1 Matamoros Felipe, José Antonio
A1 Sánchez-Puebla Fernández, Lidia
A1 Fernández Albarral, José
A1 Ramírez Sebastián, Ana Isabel
A1 Salazar Corral, Juan José
A1 Ramírez Sebastián, José Manuel
A1 Miguel Tobal, Francisco
A1 García Martín, Elena Salobrar
AB Physical activity has been shown to influence ocular health, yet the acute effects of exercise on retinal and choroidal structures remain underexplored. This prospective pre-post study evaluated 30 low-fit adults without diagnosed cardiovascular disease who underwent comprehensive ophthalmologic assessments, including OCT and OCTA imaging, before and after a submaximal aerobic capacity test. Statistically significant thinning was observed in specific retinal sectors, affecting both inner and outer layers, including the retinal pigment epithelium (RPE). Vascular analysis using the OCTAVA toolbox revealed a significant post-exercise reduction in vessel length density, total vessel length, branchpoint density and fractal dimension in the peripapillary plexus; and mean tortuosity in the macular superficial vascular complex (SVC). Choroidal thickness also showed a significant reduction in several regions. No significant changes were found in the foveal avascular zone (FAZ). These findings suggest that acute submaximal physical activity induces transient yet measurable changes in retinal and choroidal microvasculature. The results have potential implications for understanding ocular vascular dynamics and for evaluating ocular health in clinical and sports medicine contexts.
PB MDPI
YR 2025
FD 2025-09
LK https://hdl.handle.net/20.500.14352/125637
UL https://hdl.handle.net/20.500.14352/125637
LA eng
NO López-Cuenca, I.; de Hoz, R.; Elvira-Hurtado, L.; Matamoros, J.A.; Sanchez-Puebla, L.; Fernandez-Albarral, J.A.; Ramírez, A.I.; Salazar, J.J.; Ramirez, J.M.; Miguel-Tobal, F.; et al. Moderate Physical Activity Generates Changes in Retina and Choroid in Low-Fit Adults. Appl. Sci. 2025, 15, 10458. https://doi.org/10.3390/app151910458
NO Universidad Complutense de Madrid
DS Docta Complutense
RD 21 mar 2026