TY - JOUR AU - Ortiz Ortiz, Miguel Ángel AU - Morán, José M. AU - Ruiz Mesa, Luz M. AU - Bravo San Pedro, José Manuel AU - Fuentes, José M. PY - 2010 DO - 10.1093/toxsci/kfq146 SN - 1096-0929 UR - https://hdl.handle.net/20.500.14352/128824 T2 - Toxicological Sciences AB - Paraquat (PQ) is a well-known herbicide that exerts its effects by elevating intracellular levels of superoxide. It has been previously demonstrated that oxidative and nitrosative stress participate to PQ-induced cell death. Here, we document that PQ... LA - eng M2 - 614 PB - Oxford University Press KW - Paraquat KW - Neurotoxicity KW - GAPDH KW - Nuclear translocation KW - Siah KW - Nitric oxide KW - Parkinson’s disease TI - Paraquat exposure induces nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and the activation of the nitric oxide-GAPDH-Siah cell death cascade TY - journal article VL - 116 ER -