RT Journal Article
T1 The Ultratrace Determination of Fluoroquinolones in RiverWater Samples by an Online Solid-Phase Extraction MethodUsing a Molecularly Imprinted Polymer as a Selective Sorbent
A1 Baeza, A.N.
A1 Urriza-Arsuaga, Idoia
A1 Navarro Villoslada, Fernando
A1 Urraca Ruiz, Javier
AB Fluoroquinolones (FQs) are broad-spectrum antibiotics widely used to treat animal and human infections. The use of FQs in these activities has increased the presence of antibiotics in wastewater and food, triggering antimicrobial resistance, which has severe consequences for human health. The detection of antibiotics residues in water and food samples has attracted much attention. Herein, we report the development of a highly sensitive online solid-phase extraction methodology based on a selective molecularly imprinted polymer (MIP) and fluorescent detection (HPLC-FLD) for the determination of FQs in water at low ng L−1 level concentration. Under the optimal conditions, good linearity was obtained ranging from 0.7 to 666 ng L−1 for 7 FQs, achieving limits of detection (LOD) in the low ng L−1 level and excellent precision. Recoveries ranged between 54 and 118% (RSD < 17%) for all the FQs tested. The method was applied to determining FQs in river water. These results demonstrated that the developed method is highly sensitive and selective.
PB MDPI
SN 1420-3049
YR 2022
FD 2022
LK https://hdl.handle.net/20.500.14352/72199
UL https://hdl.handle.net/20.500.14352/72199
LA eng
NO MINECO
DS Docta Complutense
RD 7 abr 2025