RT Journal Article
T1 The Self-Reported Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and PainDETECT Questionnaires in COVID-19 Survivors with Post-COVID Pain
A1 Fernández de las Peñas, César
A1 Valera Calero, Juan Antonio
A1 Herrero Montes, Manuel
A1 del Valle Loarte, Pablo
A1 Rodríguez Rosado, Rafael
A1 Ferrer Pargada, Diego
A1 Arendt Nielsen, Lars
A1 Parás Bravo, Paula
AB This study aimed to analyze correlations between Self-Report Leeds Assessment of Neu-ropathic Symptoms (S-LANSS) and PainDETECT with proxies of sensitization, pain-related, or psychological/cognitive variables in coronavirus disease, 2019 (COVID-19) survivors exhibiting post-COVID pain. Demographic, clinical, psychological, cognitive, sensitization-associated symptoms, and health-related quality of life were collected in 146 survivors with post-COVID pain. The PainDE-TECT and S-LANSS questionnaires were used for assessing neuropathic pain-related symptoms. Patients were assessed with a mean of 18.8 (SD 1.8) months after hospitalization. Both questionnaires were positively associated with pain intensity (p < 0.05), anxiety (PainDETECT p < 0.05; S-LANSS p < 0.01), sensitization-associated symptoms (p < 0.01), catastrophism (p < 0.01), and kinesiophobia (p < 0.01) and negatively associated with quality of life (PainDETECT p < 0.05; S-LANSS p < 0.01). Depressive levels were associated with S-LANSS (p < 0.05) but not with PainDETECT. The step-wise regression analyses revealed that 47.2% of S-LANSS was explained by PainDETECT (44.6%), post-COVID pain symptoms duration (1.7%), and weight (1.1%), whereas 51.2% of PainDETECT was explained by S-LANSS (44.6%), sensitization-associated symptoms (5.4%), and anxiety levels (1.2%). A good convergent association between S-LANSS and PainDETECT was found. Additionally, S-LANSS was associated with symptom duration and weight whereas PainDETECT was associated with sensitization-associated symptoms and anxiety levels, suggesting that the two questionnaires evaluate different aspects of the neuropathic pain spectrum in post-COVID pain patients.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 1999-4915
YR 2022
FD 2022-07-07
LK https://hdl.handle.net/20.500.14352/135068
UL https://hdl.handle.net/20.500.14352/135068
LA eng
NO Fernández-De-las-peñas C, Valera-Calero JA, Herrero-Montes M, Del-Valle-loarte P, Rodríguez-Rosado R, Ferrer-Pargada D, et al. The Self-Reported Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and PainDETECT Questionnaires in COVID-19 Survivors with Post-COVID Pain. Viruses. 2022;14(7).
NO El proyecto contó con el apoyo de una ayuda de la Comunidad de Madrid y de la Unión Europea, a través del Fondo Europeo de Desarrollo Regional (FEDER), Recursos REACT-UE del Programa Operativo de Madrid 2014–2020, financiado como parte de la respuesta de la Unión a la pandemia de COVID‑19 (LONG-COVID-EXP-CM); de una ayuda Next-Val 2021 de la Fundación Instituto de Investigación Marqués de Valdecilla (IDIVAL); y de una ayuda de la Fundación Novo Nordisk 0067235.  Los patrocinadores no participaron en el diseño, la recogida, la gestión, el análisis o la interpretación de los datos, ni en la redacción, revisión o aprobación del manuscrito o de su contenido. Los autores fueron responsables de la decisión de enviar el manuscrito para su publicación, y el patrocinador no participó en esta decisión.
DS Docta Complutense
RD 27 abr 2026