RT Journal Article T1 Comorbidity Patterns in Patients with Chronic Diseases in General Practice A1 García Olmos, Luis A1 Salvador, Carlos H. A1 Alberquilla, Ángel A1 Lora Pablos, David A1 Carmona, Montserrat A1 García-Sagredo, Pilar A1 Pascual, Mario A1 Muñoz, Adolfo A1 Monteagudo, José Luis A1 García-López, Fernando AB Introduction: Healthcare management is oriented toward single diseases, yet multimorbidity is nevertheless the rule and there is a tendency for certain diseases to occur in clusters. This study sought to identify comorbidity patterns in patients with chronic diseases, by reference to number of comorbidities, age and sex, in a population receiving medical care from 129 general practitioners in Spain, in 2007.Methods: A cross-sectional study was conducted in a health-area setting of the Madrid Autonomous Region (Comunidad Autónoma), covering a population of 198,670 individuals aged over 14 years. Multiple correspondences were analyzed to identify the clustering patterns of the conditions targeted.Results: Forty-two percent (95% confidence interval [CI]: 41.8-42.2) of the registered population had at least one chronic condition. In all, 24.5% (95% CI: 24.3-24.6) of the population presented with multimorbidity. In the correspondence analysis, 98.3% of the total information was accounted for by three dimensions. The following four, age- and sex-related comorbidity patterns were identified: pattern B, showing a high comorbidity rate; pattern C, showing a low comorbidity rate; and two patterns, A and D, showing intermediate comorbidity rates.Conclusions: Four comorbidity patterns could be identified which grouped diseases as follows: one showing diseases with a high comorbidity burden; one showing diseases with a low comorbidity burden; and two showing diseases with an intermediate comorbidity burden. PB Public Library Science SN 1932-6203 YR 2012 FD 2012 LK https://hdl.handle.net/20.500.14352/116122 UL https://hdl.handle.net/20.500.14352/116122 LA eng NO García-Olmos L, Salvador CH, Alberquilla Á, Lora D, Carmona M, García-Sagredo P, Pascual M, Muñoz A, Monteagudo JL, García-López F. Comorbidity patterns in patients with chronic diseases in general practice. PLoS One. 2012;7(2):e32141. doi: 10.1371/journal.pone.0032141. Epub 2012 Feb 16. PMID: 22359665; PMCID: PMC3281110. DS Docta Complutense RD 6 abr 2025