RT Journal Article
T1 Utility of Bruch membrane opening-based optic nerve head parameters in myopic subjects
A1 Sastre Ibáñez, Marina
A1 Martínez De La Casa Fernández-Borrella, José María
A1 Rebolleda Fernández, Gema
A1 Cifuentes Canorea, Pilar
A1 Moreno, María Nieves
A1 Morales Fernández, Laura
A1 Sáenz Francés, Federico
A1 García Feijoo, Julián
AB Purpose: To evaluate whether the new rim analysis software with spectral-domain optical coherence tomography (SD-OCT) shows advantages over the retinal nerve fiber layer (RNFL) thickness in patients with moderate myopia.Methods: In this prospective cross-sectional study, we studied 65 healthy subjects, 37 with spherical refractive errors in the range of -3 to -6 D (moderate, G1) and 28 with less than -3 D (low/non-myopic, G0). All patients were examined with Heidelberg Spectralis SD-OCT, including Glaucoma Premium Module Edition (GPME) software. With GPME, we analyzed the neuroretinal rim (Bruch membrane opening-minimum rim width [BMO-MRW]) and RNFL.Results: The average age of subjects was 30.2 ± 9.3 years for G0 and 29.9 ± 7.1 years for G1 (p = 0.903). Mean sphere was −0.5 ± 0.3 D (-1.25 to 0 D) G0 and -3.9 ± 0.3 D (-6.00 to -3 D) G1 (p<0.001). The RNFL thickness comparison between G0 and G1 showed a significantly lower thickness in G1 (p = 0.018). The BMO-MRW measurements were similar in both groups (p = 0.331). With the BMO-MRW examination, the number of sectors classified as pathologic per subject in G1 were significantly lower compared to RNFL analysis (p = 0.023).Conclusions: Ring analysis based on BMO-MRW measurements shows a lower rate of false-positives compared to RNFL thickness when studying healthy moderate myopic eyes and it would be advisable to take this into consideration when analyzing these patients.
PB Sage Publications
SN 1120-6721
YR 2018
FD 2018-01-01
LK https://hdl.handle.net/20.500.14352/12072
UL https://hdl.handle.net/20.500.14352/12072
LA eng
NO Sastre Ibáñez, M., Martínez De La Casa Fernández-Borrella, J. M., Rebolleda Fernández, G. et al. «Utility of Bruch Membrane Opening-Based Optic Nerve Head Parameters in Myopic Subjects». European Journal of Ophthalmology, vol. 28, n.o 1, enero de 2018, pp. 42-46. DOI.org (Crossref), https://doi.org/10.5301/ejo.5001022.
NO Instituto de Salud Carlos III
NO Redes Temáticas de Investigación Cooperativa en Salud (España)
NO OFTARED
NO Universidad Complutense de Madrid
DS Docta Complutense
RD 8 abr 2025