RT Journal Article
T1 Female reproduction and the microbiota in mammals: Where are we?
A1 García García, Rosa María
A1 Arias Álvarez, María
A1 Jordán Rodríguez, Daniela
A1 Rebollar, Pilar G.
A1 Lorenzo González, Pedro Luis
A1 Herranz Sorribes, Carmen
A1 Rodríguez, Juan Miguel
AB While it is generally accepted that the mammalian vagina contains a site-specific microbiota that plays relevant roles in genital and reproductive health, the existence of an extra-vaginal microbiota in the female reproductive tract (i.e. follicular fluid, oviduct, endometrium, and placenta) is, at least, a matter of controversy. Many conclusions in this field have failed to consider the technical limitations, biases, and confounding factors inherent to next-generation sequencing (NGS) approaches. While this creates uncertainty in the field, there is no doubt this subject is set to be the focus of new research efforts because of its scientific and practical connotations in female reproductive health. The current art state, its limitations, and gaps in our knowledge about the female reproductive tract's microbiota and, particularly, about the microbes of the extra-vaginal environment are presented in this review. Also are discussed possible relationships between the gut and oral microbiota and reproductive events.
PB Elsevier
SN 0093691X
YR 2022
FD 2022-10-08
LK https://hdl.handle.net/20.500.14352/72613
UL https://hdl.handle.net/20.500.14352/72613
LA eng
NO CRUE-CSIC (Acuerdos Transformativos 2022)
DS Docta Complutense
RD 7 abr 2025