RT Journal Article T1 Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study A1 Montero Solís, Eduardo A1 Bujaldón Rodríguez, Rocío A1 Montanya, Eduard A1 Calle Pascual, Alfonso Luis A1 Rojo Martinez, Gemma A1 Castaño, Luis A1 Franch-Nadal, Joseph A1 Delgado, Elías A1 Chaves, Felipe A1 Herrera, A1 Alonso Álvarez, Bettina María A1 Sanz Alonso, Mariano A1 Herrera González, David AB Aim: To evaluate the cross-sectional association between severe periodontitis and diabetes mellitus (DM), in a representative sample of Spanish population.Materials and methods: The di@bet.es epidemiological study is a population-based cohort study aimed to determine the prevalence and incidence of DM in the adult population of Spain. The at-risk sample at the final examination (2016-2017) included 1751 subjects who completed an oral health questionnaire. This questionnaire, together with demographic and risk factors, had been previously validated to build an algorithm to predict severe periodontitis in the Spanish population. Logistic regression models were used to evaluate the association between severe periodontitis and DM with adjustment for confounding factors.Results: In total, 144 subjects developed DM, which yielded 8.2% cumulative incidence. Severe periodontitis was detected in 59.0%, 54.7% or 68.8% of the subjects depending on three different selected criteria at the 2016-2017 exam. All criteria used to define severe periodontitis were associated with DM in unadjusted analysis, but the magnitude of the association decreased after adjusting for significant confounders. The criteria '≥50% of teeth with clinical attachment loss ≥5 mm' presented an odds ratio of 4.9 (95% confidence interval: 2.2-10.7; p ≤ .001) for DM.Conclusions: Severe periodontitis is associated with DM in the Spanish population. PB Wiley SN 0303-6979 YR 2024 FD 2024-04-05 LK https://hdl.handle.net/20.500.14352/113728 UL https://hdl.handle.net/20.500.14352/113728 LA eng NO Montero E, Bujaldón R, Montanya E, Calle-Pascual AL, Rojo-Martínez G, Castaño L, Franch-Nadal J, Delgado E, Chaves F, Alonso B, Sanz M, Herrera D. Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study. J Clin Periodontol. 2024 Apr;51(4):368-379. doi: 10.1111/jcpe.13937 DS Docta Complutense RD 4 abr 2025