RT Journal Article
T1 Vermiform Appendix During the Repackaging Process from Umbilical Herniation to Fixation onto the Right Posterior Abdomen
A1 Kim, Ji Hyun
A1 Jin. Zhe W., 
A1 Shibata, Shunichi
A1 Murakami, Gen
A1 Hayashi, Shogo
A1 Rodríguez Vázquez, José Francisco
AB The anatomical position of the vermiform appendix varies among adults, and these variations are responsible for differences in the symptoms of appendicitis. However, to date no study has examined how and when these variations occur during fetal development. The present study examined horizontal sections of 27 midterm fetuses (crown rump length [CRL] 38-97 mm, gestational age approximately 8-15 weeks). There were 10 fetuses (CRL 56 mm or more) in which the cecum and appendix were in a posterosuperior site near the right kidney (postmigration phase), and 12 fetuses (CRL 39-72 mm) in which the ileocecal junction and appendix remained on the visceral surface of the liver in the anterior or anterolateral abdominal cavity (migration phase, after physiological umbilical herniation). Analysis of the 12 fetuses in the migration phase indicated that the appendix extended inferiorly in eight fetuses and superiorly in four fetuses. Likewise, a "preileal" appendix (a morphology in which the distal part of the appendix was in front of the terminal ileum) was present in eight of these fetuses. Extension of the appendix superiorly or inferiorly during the migration phase seems unrelated to the topographical relationship of the appendix with the terminal ileum at the postmigration phase in fetuses and in adults. Conversely, it seems likely that a retroileal appendix leads to a coiled appendix behind the ileocecal junction. "Guidance" by the liver surface seemed to be important for posterior migration, which ended with the ascent of the liver.
PB Wiley
SN 1098-2353
SN 0897-3806
YR 2019
FD 2019-10-14
LK https://hdl.handle.net/20.500.14352/109381
UL https://hdl.handle.net/20.500.14352/109381
LA eng
NO Kim JH, Jin ZW, Shibata S, Murakami G, Hayashi S, Rodríguez-Vázquez JF. Vermiform Appendix During the Repackaging Process from Umbilical Herniation to Fixation onto the Right Posterior Abdomen: A Study of Human Fetal Horizontal Sections. Clin Anat. 2020 Jul;33(5):667-677. doi: 10.1002/ca.23484
DS Docta Complutense
RD 20 abr 2025