RT Journal Article
T1 Macular Thickness as a Potential Biomarker of Mild Alzheimer's Disease
A1 García Martín, Elena Salobrar
A1 Rojas López, María Blanca
A1 Ramírez Sebastián, Ana Isabel
A1 Hoz Montañana, María Rosa De
A1 Salazar Corral, Juan José
A1 Yubero Pancorbo, Raquel
A1 Gil Gregorio, Pedro
A1 Triviño Casado, Alberto
A1 Ramírez Sebastián, José Manuel
AB Although several postmortem findings in the retina of patients with Alzheimer's disease (AD) are available, new biomarkers for early diagnosis and follow-up of AD are still lacking. It has been postulated that the defects in the retinal nerve fiber layer (RNFL) may be the earliest sign of AD, even before damage to the hippocampal region that affects memory. This fact may reflect retinal neuronal-ganglion cell death and axonal loss in the optic nerve in addition to aging.
PB Elsevier / American Academy of Ophthalmology
SN 0161-6420
YR 2014
FD 2014-03-18
LK https://hdl.handle.net/20.500.14352/35304
UL https://hdl.handle.net/20.500.14352/35304
LA eng
NO García Martín, E. S., Rojas López, M. B., ramírez Sebastián, A. I. et al. «Macular Thickness as a Potential Biomarker of Mild Alzheimer’s Disease». Ophthalmology, vol. 121, n.o 5, mayo de 2014, pp. 1149-1151.e3. DOI.org (Crossref), https://doi.org/10.1016/j.ophtha.2013.12.023.
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Redes Temáticas de Investigación Cooperativa
DS Docta Complutense
RD 7 abr 2025