%0 Journal Article
%A Sebastián Franco, José Luis
%A Muñoz San Martín, Sagrario
%A Sancho Ruíz, Miguel
%A Miranda Pantoja, José Miguel
%T Analysis of the electric field induced forces in erythrocyte membrane pores using a realistic cell model
%D 2006
%@ 0031-9155
%U https://hdl.handle.net/20.500.14352/50918
%X We calculate the induced electric stress forces on transient hydrophobic pores in the membrane of an erythrocyte exposed to an electric field. For this purpose, we use a finite element numerical technique and a realistic shape for the biconcave erythrocyte represented by a set of parametric equations in terms of Jacobi elliptic functions. The results clearly show that the electrical forces on the base and sidewalls of the pore favour the opening of the pore. A comparison of the force densities obtained for an unstretched flat membrane and for the realistic erythrocyte model shows that the thinning and curvature of the membrane cannot be neglected. We also show that the pore deformation depends strongly on the orientation of the pore with respect to the external field, and in particular is very small when the field is tangent to the membrane surface.
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