RT Journal Article
T1 Analysis of the electric field induced forces in erythrocyte membrane pores using a realistic cell model
A1 Sebastián Franco, José Luis
A1 Muñoz San Martín, Sagrario
A1 Sancho Ruíz, Miguel
A1 Miranda Pantoja, José Miguel
AB We calculate the induced electric stress forces on transient hydrophobic pores in the membrane of an erythrocyte exposed to an electric field. For this purpose, we use a finite element numerical technique and a realistic shape for the biconcave erythrocyte represented by a set of parametric equations in terms of Jacobi elliptic functions. The results clearly show that the electrical forces on the base and sidewalls of the pore favour the opening of the pore. A comparison of the force densities obtained for an unstretched flat membrane and for the realistic erythrocyte model shows that the thinning and curvature of the membrane cannot be neglected. We also show that the pore deformation depends strongly on the orientation of the pore with respect to the external field, and in particular is very small when the field is tangent to the membrane surface.
PB IOP Publishing Ltd
SN 0031-9155
YR 2006
FD 2006-12-07
LK https://hdl.handle.net/20.500.14352/50918
UL https://hdl.handle.net/20.500.14352/50918
LA eng
NO © IOP Publishing Ltd. This work was supported by the Comunidad de Madrid under Grant number: PR45/05-14166.
NO Comunidad de Madrid
DS Docta Complutense
RD 8 jun 2025