TY  - JOUR
AU  - Villalvazo, Priscila
AU  - Marzal Alfaro, Belén
AU  - García Alfonso, María Pilar
AU  - Revuelta Herrero, José Luis
AU  - Thomas, Fabienne
AU  - López Tarruella, Sara
AU  - García González, Xandra
AU  - Calvo, Aitana
AU  - Yakoubi, Malika
AU  - Salvador Martín, Sara
AU  - López López, Flora
AU  - Aguilar, Iker
AU  - Sanjurjo Sáez, María
AU  - Martín, Miguel
AU  - López Fernández, Luis Andrés
PY  - 2021
DO  - 10.3390/jpm11080792
SN  - 2075-4426
UR  - https://hdl.handle.net/20.500.14352/4833
T2  - Journal of Personalized Medicine
AB  - Dihydropyrimidine dehydrogenase deficiency is a major cause of severe fluoropyrimidine-induced toxicity and could lead to interruption of chemotherapy or life-threatening adverse reactions. This study aimed to characterize the DPYD exon sequence, mRNA...
LA  - eng
M2  - 792
PB  - MPDI
KW  - pharmacogenetics
KW  - cancer
KW  - adverse drug events
KW  - capecitabine
KW  - 5-fluorouracil
TI  - DPYD Exome, mRNA Expression and Uracil Levels in Early Severe Toxicity to Fluoropyrimidines: An Extreme Phenotype Approach
TY  - journal article
VL  - 11
ER  -