RT Journal Article
T1 Synthesis of ketones by C-H functionalization of aldehydes with boronic acids under transition-metal-free conditions
A1 García Csaky, Aurelio
A1 Roscales García, Silvia
AB A method for the synthesis of ketones from aldehydes and boronic acids via a transition-metal-free C−H functionalization reaction is reported. The method employs nitrosobenzene as a reagent to drive the simultaneous activation of the boronic acid as a boronate and the activation of the C−H bond of the aldehyde as an iminium species that triggers the key C−C bond-forming step via an intramolecular migration from boron to carbon. These findings constitute a practical, scalable, and operationally straightforward method for the synthesis of ketones.
PB Wiley
SN 1521-3773
YR 2021
FD 2021-01
LK https://hdl.handle.net/20.500.14352/113460
UL https://hdl.handle.net/20.500.14352/113460
LA eng
NO Angew. Chem. Int. Ed. 2021, 60, 8728
NO Ministerio de Ciencia, Innovación y Universidades
DS Docta Complutense
RD 2 abr 2025