RT Journal Article
T1 Correlations between corneal and optic nerve head variables in healthy subjects and patients with primary open angle glaucoma
A1 Saenz Frances, Federico
A1 Jañez Escalada, Luis
A1 Borrego Sanz, Lara
A1 Berrozpe Villabona, Clara
A1 Martínez de la Casa, Jose Maria
A1 Morales Fernández, Laura
A1 García Sánchez, Julián
A1 Santos Bueso, Enrique
A1 García Feijoo, Julián
AB AIM: To correlate corneal variables (determined using the Pentacam) with optic nerve head (ONH) variables determined using the Heidelberg retina tomograph (HRT) in healthy subjects and patients diagnosed with primary open angle glaucoma (POAG).METHODS: Measurements were made in 75 healthy eyes and 73 eyes with POAG and correlations examined through Pearson correlation coefficients between the two sets of variables in the two subject groups. The corneal variables determined were corneal volume (CVol), central corneal thickness (CCT), overall corneal thickness (OvCT), the mean thickness of a circular zone centered at the corneal apex of 1 mm radius (zone I) and the mean thickness of several concentric rings, also centered at the apex until the limbus, each of 1 mm width (zones II to VI respectively). The ONH variables were determined using the HRT.RESULTS: The following pairs of variables were correlated in the control group: CCT-disc area (DAr) (-0.48; P<0.0001), Zone I-DAr (-0.503; P<0.0001) and Zone II-DAr (-0.443; P<0.0001); and in the POAG group: CCT-cup-to-disc area ratio (CDRa) (-0.402; P<0.0001), Zone I-CDRa (-0.418; P<0.0001), Zone II-CDRa (-0.405; P=0.006), Zone I-cup shape measure (CSM) (-0.415; P=0.002), Zone II-CSM (-0.405; P=0.001), Zone IV-height variation contour (HVC) (0.378; P=0.002); Zone V-HVC (0.388, P<0.0001).CONCLUSION: AS-OCT-derived lens thickness measurement is valid and comparable to the results obtained by A-scan US. It can be used as a reliable noncontact method for measuring lens thickness in adults with or without significant cataract.
PB Press of International Journal of Ophthalmology
SN 2222-3959
YR 2015
FD 2015-12-18
LK https://hdl.handle.net/20.500.14352/23131
UL https://hdl.handle.net/20.500.14352/23131
LA eng
NO En O.A. en la web del editor.
NO Instituto de Salud Carlos III de Madrid
DS Docta Complutense
RD 1 may 2024