RT Journal Article
T1 Effect of time-dependent ibuprofen administration on the post operatory after impacted third molar extraction: a cross-over randomized controlled trial
A1 Pérez González, Fabián
A1 Abusamak, Mohammad
A1 Sáez Alcaide, Luis Miguel
A1 Torres García Denche, Jesús
A1 Marino, Faleh Ahmad Tamimi
AB Purpose: To evaluate time-dependent administration of ibuprofen in a lower third molar extraction model. Methods: Eleven patients requiring bilateral surgical removal of lower third molars were recruited and randomized into a blinded crossover randomized controlled trial. For 3 days after surgery, the control group was prescribed ibuprofen 400 mg every 8 h. On the other hand, the experimental group received also ibuprofen 400 mg at breakfast and lunch, replacing the dinner intake with a placebo. Pain measurements (Visual Analog Scale from 0 to 10) were recorded at baseline, 24, 48, and 72 h postoperatively. Facial swelling and trismus were also measured at baseline, 24, and 72 h postoperatively.Results: Postoperative swelling and pain perception did not show signifcative diference between the control and experimental groups at 24, 48, and 72 h. Trismus was signifcantly lower in the control group than in the experimental group at 72 h postoperatively (p=0.008). Rescue medication consumption seemed to be comparable between groups. Conclusion: Eliminating night time ibuprofen might be insignifcant for pain control after third molar extraction.
PB Springer Nature
SN 1865-1569
YR 2022
FD 2022-08-03
LK https://hdl.handle.net/20.500.14352/71885
UL https://hdl.handle.net/20.500.14352/71885
LA eng
NO Pérez-González F, Abusamak M, Sáez-Alcaide LM, et al (2022) Effect of time-dependent ibuprofen administration on the post operatory after impacted third molar extraction: a cross-over randomized controlled trial. Oral Maxillofac Surg 27:699–706. https://doi.org/10.1007/s10006-022-01104-8
NO CRUE-CSIC (Acuerdos Transformativos 2022)
DS Docta Complutense
RD 20 abr 2025