RT Journal Article T1 Chronic primary intestinal pseudo-obstruction from visceral myopathy A1 Muñoz Yagüe, María Teresa A1 Marín Gabriel, José Carlos A1 Colina Ruiz-Delgado, Francisco A1 Ibarrola De Andrés, Carolina Natalia A1 López Alonso, G. A1 Martín, M. A. A1 Solís Herruzo, José Antonio AB Chronic intestinal pseudo-obstruction is an uncommon syndrome characterized by relapsing episodes suggesting intestinal obstruction during which no mechanical causes are identified to account for symptoms. Etiologic factors may be manifold. Among them a number of neurologic conditions, gastrointestinal smooth muscle myopathies, endocrino-metabolic and autoimmune diseases, and the use of selected drugs stand out. We report a case of chronic intestinal pseudo-obstruction originating in a sporadic, primary intestinal myopathy that corresponds to no type thus far described. A histological study of the intestinal wall showed disrupted muscle bundles and the presence of interstitial edema. Myocytes had severe degenerative changes, and no alterations were seen in submucosal and myenteric plexus neurons. The activity of enzyme complexes in the mitochondrial respiratory chain, and of thymidine phosphorylase was normal. No mitochondrial DNA changes were seen. PB Sociedad Española de Patología Digestiva SN 1130-0108 YR 2006 FD 2006 LK https://hdl.handle.net/20.500.14352/130767 UL https://hdl.handle.net/20.500.14352/130767 LA eng NO Muñoz-Yagüe MT, Marín JC, Colina F, Ibarrola C, López-Alonso G, Martín MA, Solís-Herruzo JA. Chronic primary intestinal pseudo-obstruction from visceral myopathy. Rev Esp Enferm Dig. 2006 Apr;98(4):292-302. English, Spanish. doi: 10.4321/s1130-01082006000400007 DS Docta Complutense RD 22 mar 2026