RT Journal Article
T1 Effect of a combination of telmisartan and amlodipine in hypertensive dogs
A1 Caro Vadillo, Alicia
A1 Daza-González, María Angeles
A1 González Alonso-Alegre, Elisa-Margarita
A1 Rodríguez Álvaro, Alfonso
A1 Gómez-García, José
AB Systemic hypertension (SHT) in dogs is considered a health risk factor. Telmisartan is a well-known antihypertensive agent in humans. There are limited reports about its efficacy in dogs. Five dogs with primary and secondary SHT refractory to the combined treatment of benazepril and amlodipine had a successful control of systolic arterial blood pressure (SBP) when telmisartan was combined with amlodipine. SBP showed a significant reduction after any treatment, but only reached successful control when amlodipine plus telmisartan was administered (median SBP: 215 mmHg before treatment [min-max: 180-240 mmHg]; 180 mmHg for amlodipine plus benazepril treatment [min-max: 170-210 mmHg]; 142 mmHg after amlodipine plus telmisartan treatment [min-max: 120-165 mmHg]). This control remained stable in the long-term follow-up (average 5.2 months). In the cases reported, the telmisartan plus amlodipine treatment showed good efficacy in the control of SHT, regardless of cause, and was well tolerated in all patients.
PB Wiley
SN 2052-6121
YR 2018
FD 2018-05-26
LK https://hdl.handle.net/20.500.14352/113344
UL https://hdl.handle.net/20.500.14352/113344
LA eng
NO Caro-Vadillo A, Daza-González mA, Gonzalez-Alonso-Alegre e, et al. Vet Rec Case Rep published online First: 5/26/2018. doi:10.1136/ vetreccr-2017-000471
NO Contributors Conception or design of the work: ACV, MADG, JGG. Data collection: ACV, MADG, EGAA, AR. Data analysis and interpretation: ACV, MADG, JGG. Drafting the article: ACV, MADG, EGAA, AR, JGG. Critical revision of the article: ACV, JGG. Final approval of the version to be published: ACV, MADG, EGAA, AR, JGG.
DS Docta Complutense
RD 10 abr 2025