TY - JOUR AU - Sánchez Sánchez, Roberto AU - Imhof, Dennis AU - Hecker, Yanina Paola AU - Ferré Pérez, Ignacio AU - Re, Michela Tatiana AU - Moreno Gonzalo, Javier AU - Blanco Murcia, Francisco Javier AU - Mejías López, Elena AU - Hulverson, Matthew A. AU - Choi, Ryan AU - Arnold, Samuel L. M. AU - Ojo, Kayode K. AU - Barrett, Lynn K. AU - Hemphill, Andrew AU - Van Voorhis, Wesley C. AU - Ortega Mora, Luis Miguel PY - 2023 DO - 10.1093/infdis/jiad470 SN - 0022-1899 UR - https://hdl.handle.net/20.500.14352/104468 T2 - The Journal of Infectious Diseases AB - Congenital toxoplasmosis in humans and in other mammalian species, such as small ruminants, is a well-known cause of abortion and fetal malformations. The calcium-dependent protein kinase 1 (CDPK1) inhibitor BKI-1748 has shown a promising safety... LA - eng M2 - 558 PB - Oxford University Press KW - Toxoplasma gondii KW - One health therapeutics KW - BKI-1748 KW - Congenital toxoplasmosis KW - Sheep KW - Safety KW - Efficacy TI - An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii TY - journal article VL - 229 ER -