RT Journal Article
T1 Genome-wide population affinities and signatures of adaptation in hydruntines, sussemiones and Asian wild asses
A1 Pan, Jianfei
A1 Liu, Xuexue
A1 Baca, Mateusz
A1 Calvière-Tonasso, Laure
A1 Schiavinato, Stéphanie
A1 Chauvey, Loreleï
A1 Tressières, Gaétan
A1 Arsuaga Ferreras, Juan Luis
A1 Lira Garrido, Jaime
AB The extremely rich palaeontological record of the horse family, also known as equids, has provided many examples of macroevolutionary change over the last ~55 Mya. This family is also one of the most documented at the palaeogenomic level, with hundreds of ancient genomes sequenced. While these data have advanced understanding of the domestication history of horses and donkeys, the palaeogenomic record of other equids remains limited. In this study, we have generated genome-wide data for 25 ancient equid specimens spanning over 44 Ky and spread across Anatolia, the Caucasus, Central Asia and Mongolia. Our dataset includes the genomes from two extinct species, the European wild ass, Equus hydruntinus, and the sussemione Equus ovodovi. We document, for the first time, the presence of sussemiones in Mongolia and their survival around ~3.9 Kya, a finding that should be considered when discussing the timing of the first arrival of the domestic horse in the region. We also identify strong spatial differentiation within the historical ecological range of Asian wild asses, Equus hemionus, and incomplete reproductive isolation in several groups yet considered as different species. Finally, we find common selection signatures at ANTXR2 gene in European, Asian and African wild asses. This locus, which encodes a receptor for bacterial toxins, shows no selection signal in E. ovodovi, but a 5.4-kb deletion within intron 7. Whether such genetic modifications played any role in the sussemione extinction remains unknown.
PB Wiley
SN 0962-1083
YR 2024
FD 2024-09-16
LK https://hdl.handle.net/20.500.14352/120362
UL https://hdl.handle.net/20.500.14352/120362
LA eng
NO Pan, J., Liu, X., Baca, M., Calvière‐Tonasso, L., Schiavinato, S., Chauvey, L., Tressières, G., Perdereau, A., Aury, J., Oliveira, P. H., Wincker, P., Abdykanova, A., Arsuaga, J. L., Bayarsaikhan, J., Belinskiy, A. B., Carbonell, E., Davoudi, H., Lira Garrido, J., Gilbert, A. S., … Orlando, L. (2024). Genome‐wide population affinities and signatures of adaptation in hydruntines, sussemiones and Asian wild asses. Molecular Ecology, 33(19), e17527. https://doi.org/10.1111/mec.17527
DS Docta Complutense
RD 25 feb 2026