RT Journal Article
T1 Biochemical properties and biotechnological applications of microbial enzymes involved in the degradation of polyester-type plastics
A1 Urbanek, Aneta K.
A1 Mirończuk, Aleksandra M.
A1 García Martín, Alberto
A1 Saborido Modia, Ana Isolina
A1 De La Mata Riesco, Mª Isabel
A1 Arroyo Sánchez, Miguel
AB Application of polyester-degrading enzymes should be considered as an eco-friendly alternative to chemical recycling due to the huge plastic waste disposal nowadays. Many hydrolases from several fungi and bacteria have been discovered and successfully evaluated for their activity towards different aliphatic polyesters (PHA, PBS, PBSA, PCL, PLA), aromatic polyesters (PET, PBT, PMT) as well as their co-polyesters (PBST, PBAT, PBSTIL). This revision gives an up-to-date overview on the main biochemical features and biotechnological applications of those reported enzymes which are able to degrade polyester-based plastics, including different microbial polyester depolymerases, esterases, cutinase-like enzymes and lipases. Summarized information includes available protein sequences with the corresponding accession numbers deposited in NCBI server, 3D resolved structures, and data about optimal conditions for enzymatic activity and stability of many of these microbial enzymes that would be helpful for researchers in this topic. Although screening and identification of new native polyester hydrolases from microbial sources is undeniable according to literature, we briefly highlight the importance of the design of improved enzymes towards recalcitrant aromatic polyesters through different approaches that include site-directed mutagenesis and surface protein engineering.
PB Elsevier
SN 0006-3002
YR 2019
FD 2019-11-16
LK https://hdl.handle.net/20.500.14352/6396
UL https://hdl.handle.net/20.500.14352/6396
LA eng
NO Ministerio de Economía y Competitividad (MINECO)
NO Polish National Agency for Academic Exchange
DS Docta Complutense
RD 20 abr 2025