RT Journal Article
T1 Comparative anatomy of the subclavius muscle and clavicle: a histological study using human, swine and mouse fetuses
A1 Verdugo López, Samuel
A1 Kitamura, Kei
A1 Murakami, Gen
A1 Rodríguez-Vázquez, Jose Francisco
A1 Yamamoto, Hitoshi
AB Background: Some mammals including the swine carry a fibrous vestigial clavicle, but a subclavius muscle (SBM) extends between the first rib and the supraspinatus muscle surface fascia. We aimed to examine development of the SBM and clavicle for finding a specific factor to provide the curious morphology.Materials and methods: Histological sections of early- and midterm fetuses of the swine, human and mouse were observed and compared at the almost same morphological stage. Results: In all three species, the initial SBM was seen extending between the cartilaginous first rib and a mesenchymal clavicle. At the early stage, the human and mouse fetuses carried the mesenchymal manubrium sterni above the heart bulbus as well as the acromion above the humeral head. However, in the swine fetus, the manubrium remained far caudal to the first rib, while the acromion was in the laterocaudal side of the glenohumeral joint. In place of the acromion, the swine supraspinatus muscle was large and covered the humeral head. At midterm, the human and mouse SBM attached to the membranous bone of the clavicle. Endochondral ossification occurred at the lateral and medial ends of the human clavicle, while it was seen in the medial half of the mouse clavicle anlage with a homogenous eosinophilic matrix.Conclusions: The swine clavicle seemed to lose the endochondral parts due to the caudally-shifted manubrium sterni and acromion. The medial or clavicular attachment of the swine SBM might migrate to a nearby fascia of the supraspinatus muscle in the later development.
PB Polish Anatomical Society
SN 0015-5659
YR 2025
FD 2025-01-02
LK https://hdl.handle.net/20.500.14352/124313
UL https://hdl.handle.net/20.500.14352/124313
LA eng
NO Verdugo-López S, Kitamura K, Murakami G, Rodríguez-Vázquez JF, Yamamoto H. Comparative anatomy of the subclavius muscle and clavicle: a histological study using human, swine and mouse fetuses. Folia Morphologica. 2025 [Epub ahead of print Jan 2, 2025]. doi:10.5603/fm.102531.
NO Versión postprint del artículo
DS Docta Complutense
RD 20 oct 2025