RT Journal Article T1 Sharp Wave Ripples in Alzheimer's Disease: In Search of Mechanisms A1 Sánchez-Aguilera López, Alberto A1 Quintanilla, Juan Pablo AB Alzheimer's disease (AD) is the most common cause of dementia. The disease is associated with the presence of plaques and neurofibrillary tangles in the brain, which leads to synaptic and neuronal degeneration and progressive learning and memory impairment (Spires-Jones and Hyman, 2014). Work of the last decades has produced a variety of diagnostic tools and treatment alternatives, yet the mechanisms underlying the disease are poorly understood, and interventions are still minimally effective, possibly in part because they are started after irreversible damage has been done. Identifying early markers of AD might therefore advance therapeutic development and effectiveness. PB Society for Neuroscience SN 1529-2401 YR 2021 FD 2021 LK https://hdl.handle.net/20.500.14352/96035 UL https://hdl.handle.net/20.500.14352/96035 LA eng NO Alberto Sanchez-Aguilera, Juan P Quintanilla. Sharp Wave Ripples in Alzheimer's Disease: In Search of Mechanisms. J Neurosci. 2021 Feb 17;41(7):1366-1370. DS Docta Complutense RD 9 abr 2025