TY - JOUR AU - Fernández, Adrián AU - Navarro Zapata, Alfonso AU - Escudero, Adela AU - Matamala, Nerea AU - Ruz Caracuel, Beatriz AU - Mirones, Isabel AU - Pernas, Alicia AU - Cobo, Marta AU - Casado, Gema AU - Lanzarot, Diego AU - Rodríguez Antolín, Carlos AU - Vela, María AU - Ferreras, Cristina AU - Mestre, Carmen AU - Viejo, Aurora AU - Leivas, Alejandra AU - Martínez, Joaquín AU - Fernández, Lucía AU - Pérez Martínez, Antonio PY - 2021 DO - 10.3390/cancers13030577 SN - 2072-6694 UR - https://hdl.handle.net/20.500.14352/7352 T2 - Cancers AB - Natural killer (NK) cells represent promising tools for cancer immunotherapy. We report the optimization of an NK cell activation–expansion process and its validation on clinical-scale. Methods: RPMI-1640, stem cell growth medium (SCGM), NK MACS and... LA - eng M2 - 577 PB - MDPI KW - NK cell immunotherapy KW - NK cell activation and expansion KW - NKAE cells KW - Clinical-grade manufacturing KW - CliniMACS Prodigy TI - Optimizing the Procedure to Manufacture Clinical-Grade NK Cells for Adoptive Immunotherapy TY - journal article VL - 13 ER -