RT Journal Article
T1 Infectious complications following major heart surgery from the day of the surgery to hospital discharge
A1 Pérez Granda, María Jesús
A1 Barrio, José María
A1 Cuerpo, Gregorio
A1 Valerio Minero, Maricela
A1 Muñoz García, Patricia Carmen
A1 Hortal Iglesias, Francisco Javier
A1 González Pinto, Ángel Tomás
A1 Bouza Santiago, Emilio
A1 Quintana, Begoña
A1 Sánchez, Alejandro Garrido
A1 Barranco, Mónica
A1 Perez, Eduardo Sánchez
A1 Moraga, Francisco
A1 López, Alba
A1 Bono, Patricia
A1 López, Ignacio Fernández
A1 Bernal, Guillermo Rodríguez
A1 Novoa, Enma
A1 Abella, Roberto Hugo Rodríguez
A1 Ruiz, Manolo
A1 Pedraz, Alvaro
A1 Diaz, Diego Monzón
A1 Fortuny, Ramón
A1 Lega, Javier Rodríguez
A1 Gallardo, Maria Yolanda Villa
A1 Calvo, Laura Diaz
A1 Gallego, Sara Solís
A1 Mere, Carmen Garcia
A1 Tomás, Alvaro Alvarez
AB BackgroundAt some point in their lives, many people will require major heart surgery (MHS). Patients are generally older adults with various risk factors for infection. However, the incidence of infection after MHS is poorly known, as reported infection data are frequently biased due to different factors like the surgical procedure, postoperative timing, and infectious syndromes or etiologic agents, among others. In addition, most patient data are retrospectively obtained.Purpose and methodsData were prospectively collected regarding the incidence of all nosocomial infections produced from the time of surgery to hospital discharge in a cohort of 800 adults consecutively undergoing a MHS procedure.ResultsDuring postoperative hospitalization, 124 of the 800 participants developed one or more infections (15.5%): during their ICU stay in 68 patients (54.8%), during their stay on the general ward post ICU in 50 (40.3%), and during their stay in both wards in 6 (4.8%). The most common infections were pneumonia (related or not to mechanical ventilation), surgical site and bloodstream. As etiological agents, 193 pathogens were isolated: mostly Gram-negative bacilli (54.4%), followed by Gram-positive bacteria (30%), viruses (4.6%) and fungi (1.5%). In our cohort, all-cause mortality was recorded in 33 participants (4.1%) and 9 infection-related deaths (1.1%) were produced. Among subjects who developed infections, overall mortality was 13.7% and in those who did not, this was only 2.3%.ConclusionInfection following MHS remains frequent and severe. Our data suggest that hospital-acquired infection studies should consider episodes of infection in all populations during their entire hospital stay and not only those related to specific clinical syndromes or acquired while the patient is in intensive care.
PB BioMed Central Ltd
SN 1471-2334
YR 2024
FD 2024-06-11
LK https://hdl.handle.net/20.500.14352/119296
UL https://hdl.handle.net/20.500.14352/119296
LA eng
NO Pérez-Granda MJ, Barrio JM, Cuerpo G, Valerio M, Muñoz P, Hortal J, et al. Infectious complications following major heart surgery from the day of the surgery to hospital discharge. BMC Infectious Diseases. 2024;24(1).
NO Apoyado en parte por CIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058) y por subvenciones del Fondo de Investigación Sanitaria del Instituto de Salud Carlos III (PI18/01741). Financiado parcialmente por el Fondo Europeo de Desarrollo Regional (FEDER) “Una manera de hacer Europa”. Los financiadores no tuvieron ningún papel en el diseño del estudio, la recopilación y análisis de datos, la decisión de publicar ni en la preparación del manuscrito.
DS Docta Complutense
RD 22 ene 2026