%0 Journal Article
%A Viso Beronda, Alma
%A Fernández de la Pradilla Sainz de Aja, Roberto
%A Flores Aguilar-Amat, Aída
%A Águila Sánchez, Miguel Ángel del
%T Highly diastereoselective Barbier allylation and iminium cyclization: a simple entry to bicyclic and tricyclic piperazinones
%D 2008
%U https://hdl.handle.net/20.500.14352/99303
%X Barbier allylation of 5,6-dihydropyrazin-2(1H)-ones leads to a single isomer of 3-allylpiperazin-2-ones in high yields. Further Pictet–Spengler–Grieco cyclization of 3-allylpiperazin-2-ones with aldehydes provides bicyclic and tricyclic piperazinones with high diastereoselectivity.
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