RT Journal Article
T1 Highly diastereoselective Barbier allylation and iminium cyclization: a simple entry to bicyclic and tricyclic piperazinones
A1 Viso Beronda, Alma
A1 Fernández de la Pradilla Sainz de Aja, Roberto
A1 Flores Aguilar-Amat, Aída
A1 Águila Sánchez, Miguel Ángel del
AB Barbier allylation of 5,6-dihydropyrazin-2(1H)-ones leads to a single isomer of 3-allylpiperazin-2-ones in high yields. Further Pictet–Spengler–Grieco cyclization of 3-allylpiperazin-2-ones with aldehydes provides bicyclic and tricyclic piperazinones with high diastereoselectivity.
PB Elsevier
YR 2008
FD 2008-12-15
LK https://hdl.handle.net/20.500.14352/99303
UL https://hdl.handle.net/20.500.14352/99303
LA eng
NO Viso A, Fernández De La Pradilla R, Flores A, Del Águila MA. Highly diastereoselective Barbier allylation and iminium cyclization: a simple entry to bicyclic and tricyclic piperazinones. Tetrahedron 2008;64:11580–8. https://doi.org/10.1016/j.tet.2008.10.034
NO Dirección General de Ingresos
NO Comunidad de Madrid
DS Docta Complutense
RD 9 abr 2025