TY  - JOUR
AU  - Desdín-Micó, Gabriela
AU  - Soto-Heredero, Gonzalo
AU  - Aranda Gómez, Juan Francisco
AU  - Oller, Jorge
AU  - Carrasco, Elisa
AU  - Gabandé-Rodríguez, Enrique
AU  - Blanco, Eva Maria
AU  - Alfranca, Arantzazu
AU  - Cussó, Lorena
AU  - Desco, Manuel
AU  - Ibañez, Borja
AU  - Gortazar, Arancha
AU  - Fernández-Marcos, Pablo
AU  - Navarro, Maria 
AU  - Hernaez, Bruno
AU  - Alcamí, Antonio
AU  - Baixauli,  Francesc
AU  - Mittelbrunn, María
PY  - 2020
DO  - 10.1126/science.aax0860
SN  - 0036-8075
UR  - https://hdl.handle.net/20.500.14352/95026
AB  - The effect of immunometabolism on age-associated diseases remains uncertain. In this work, we show that T cells with dysfunctional mitochondria owing to mitochondrial transcription factor A (TFAM) deficiency act as accelerators of senescence. In mice,...
LA  - eng
M2  - 1371
PB  - Science
TI  - T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
TY  - journal article
VL  - 368
ER  -