RT Journal Article
T1 Nervus terminalis and nerves to the vomeronasal organ: a study using human fetal specimens
A1 Jin, Zhe Wu
A1 Cho, Kwang Ho
A1 Shibata, Shunichi
A1 Yamamoto, Masahito
A1 Murakami, Gen
A1 Rodríguez Vázquez, José Francisco
AB The human nervus terminalis (terminal nerve) and the nerves to the vomeronasal organ (VNON) are both associated with the olfactory nerves and are of major interest to embryologists. However, there is still limited knowledge on their topographical anatomy in the nasal septum and on the number and distribution of ganglion cells along and near the cribriform plate of the ethmoid bone. We observed serial or semiserial sections of 30 fetuses at 7-18 weeks (crown rump length [CRL], 25-160 mm). Calretinin and S100 protein staining demonstrated not only the terminal nerve along the anterior edge of the perpendicular lamina of the ethmoid, but also the VNON along the posterior edge of the lamina. The terminal nerve was composed of 1-2 nerve bundles that passed through the anterior end of the cribriform plate, whereas the VNON consisted of 2-3 bundles behind the olfactory nerves. The terminal nerve ran along and crossed the posterior side of the nasal branch of the anterior ethmoidal nerve. Multiple clusters of small ganglion cells were found on the lateral surfaces of the ethmoid's crista galli, which are likely the origin of both the terminal nerve and VNON. The ganglions along the crista galli were ball-like and 15-20 µm in diameter and, ranged from 40-153 in unilateral number according to our counting at 21-µm-interval except for one specimen (480 neurons; CRL, 137 mm). An effect of nerve degeneration with increasing age seemed to be masked by a remarkable individual difference.
PB Korean Association of Anatomists
SN 2093-3665
YR 2019
FD 2019
LK https://hdl.handle.net/20.500.14352/109204
UL https://hdl.handle.net/20.500.14352/109204
LA eng
NO Jin ZW, Cho KH, Shibata S, Yamamoto M, Murakami G, Rodríguez-Vázquez JF. Nervus terminalis and nerves to the vomeronasal organ: a study using human fetal specimens. Anat Cell Biol. 2019 Sep;52(3):278-285. doi: 10.5115/acb.19.020
DS Docta Complutense
RD 5 abr 2025