RT Journal Article
T1 Multifocal contact lenses for preoperative simulation of enhanced monofocal and extended depth of focus intraocular lenses using adaptive optics
A1 Giacopinelli, Luca
A1 Carrasco Rojo, Silvia
A1 Ould Haddi, Inas Baoud
A1 Albarrán Diego, César
A1 Garzón Jiménez, Nuria
A1 García Montero, María
AB PurposeTo evaluate whether multifocal contact lenses (CLs) can serve as preoperative simulators of postoperative vision with enhanced monofocal and extended depth of focus (EDOF) intraocular lenses (IOLs), using the SimVis Gekko™ adaptive-optics visual simulator.MethodsTwenty-four presbyopic subjects (mean age 54.9 ± 5.0 years; range 46-63) underwent monocular simulation of two daily disposable multifocal CLs (1-Day Acuvue® Moist Multifocal, medium addition; and Biotrue® ONEday for Presbyopia, high addition) and two IOLs (Tecnis® Eyhance™, enhanced monofocal; and LuxSmart™, EDOF) using the SimVis Gekko™ under photopic conditions and a fixed 3 mm pupil aperture. Monocular defocus curves were obtained from -3.00 to +1.00 D in 0.50 D steps. Area under the curve (AUC), negative-defocus cutoff at the 0.2 logMAR threshold, and defocus slopes from linear mixed-effects models were compared across lens conditions for both raw and offset corrected datasets.ResultsBoth CLs exhibited a systematic -0.50 D myopic offset relative to the IOL simulations, consistent with their center-near design. After applying a +0.50 D vergence correction, AUC values were comparable across all four designs (p = 0.18). At the 0.2 logMAR threshold, LuxSmart showed the widest functional range (cutoff -2.38 ± 0.66 D) and Biotrue the narrowest (-1.69 ± 0.53 D). Mixed-effects modeling indicated equivalent defocus slopes between 1-Day Acuvue Moist and Tecnis Eyhance after vergence alignment (p = 0.894), while LuxSmart showed greater defocus tolerance and Biotrue degraded significantly faster (p = 0.005).ConclusionsOnce the intrinsic -0.50 D myopic offset is compensated, the 1-Day Acuvue Moist Multifocal closely replicates the through-focus visual performance of the Tecnis Eyhance IOL, supporting its use as a practical preoperative simulator for patients being considered for enhanced monofocal implantation. Multifocal CLs combined with adaptive optics simulation may assist surgeons in tailoring IOL selection and improve shared decision-making before cataract surgery.
PB Elsevier
SN 1367-0484
YR 2026
FD 2026-05
LK https://hdl.handle.net/20.500.14352/136855
UL https://hdl.handle.net/20.500.14352/136855
LA eng
NO Giacopinelli, Luca, et al. «Multifocal Contact Lenses for Preoperative Simulation of Enhanced Monofocal and Extended Depth of Focus Intraocular Lenses Using Adaptive Optics». Contact Lens and Anterior Eye, vol. 49, n.o 3, junio de 2026, p. 102665. DOI.org (Crossref), https://doi.org/10.1016/j.clae.2026.102665.
NO Ministerio de Ciencia e Innovación (España)
DS Docta Complutense
RD 14 jun 2026