RT Journal Article
T1 Epithelioid hemangioendothelioma of the liver
A1 García Botella, Alejandra María
A1 Díez Valladares, Luis Ignacio
A1 Martín Antona, Esteban
A1 Sánchez Pernaute, Andrés
A1 Pérez Aguirre, María Elia
A1 Ortega Medina, Luis
A1 Rodríguez González, Ricardo
A1 Balibrea Cantero, José Luis
AB Epithelioid hemangioendothelioma (EH) is a rare tumor of vascular origin, which occurs at sites such as soft tissues, liver, or lung, and has a highly unpredictable malignant potential. It is an intermediate entity between well-differentiated hemangioma and angiosarcoma. We present two cases of this rare disease in which the tumor was detected fortuitously and the definitive diagnosis was based on histological evidence. Both our cases are highly illustrative of the two ways in which hepatic EH can present (nodular or diffuse) and of its diagnostic and therapeutic management. Neoplastic cells expressed the factor VIII-related antigen, CD31 or CD34. Treatment was surgical resection in one patient and liver transplant in the other. Although EH of the liver has a better prognosis than other hepatic neoplasms, conservative treatment is not recommended. Our cases highlight the importance of a histological diagnosis to avoid it being mistaken for another entity.
PB Springer Nature
SN 0944-1166
SN 1436-0691
YR 2006
FD 2006-03-23
LK https://hdl.handle.net/20.500.14352/129718
UL https://hdl.handle.net/20.500.14352/129718
LA eng
NO García-Botella, A., Díez-Valladares, L., Martín-Antona, E. et al. Epithelioid hemangioendothelioma of the liver. J Hepatobiliary Pancreat Surg 13, 167–171 (2006). https://doi.org/10.1007/s00534-005-1021-0
DS Docta Complutense
RD 18 mar 2026