RT Journal Article
T1 A New Biocompatible and Antibacterial Phosphate Free Glass-Ceramic for Medical Applications
A1 Cabal, Belén
A1 Alou Cervera, Luis
A1 Cafini, Fabio
A1 Couceiro, Ramiro
A1 Sevillano Fernández, David
A1 Esteban Tejeda, Leticia
A1 Guitián, Francisco
A1 Torrecillas, Ramón
A1 Moya, José S.
AB In the attempt to find valid alternatives to classic antibiotics and in view of current limitations in the efficacy of antimicrobial-coated or loaded biomaterials, this work is focused on the development of a new glass-ceramic with antibacterial performance together with safe biocompatibility. This bactericidal glass-ceramic composed of combeite and nepheline crystals in a residual glassy matrix has been obtained using an antimicrobial soda-lime glass as a precursor. Its inhibitory effects on bacterial growth and biofilm formation were proved against five biofilm-producing reference strains. The biocompatibility tests by using mesenchymal stem cells derived from human bone indicate an excellent biocompatibility.
PB Nature
SN 2045-2322
YR 2014
FD 2014-06-25
LK https://hdl.handle.net/20.500.14352/106086
UL https://hdl.handle.net/20.500.14352/106086
LA eng
NO Cabal B, Alou L, Cafini F, Couceiro R, Sevillano D, Esteban-Tejeda L, Guitián F, Torrecillas R, Moya JS. A new biocompatible and antibacterial phosphate free glass-ceramic for medical applications. Sci Rep. 2014 Jun 25;4:5440.
NO Ministerio de Economía y Competitividad (España)
NO Consejo Superior de Investigaciones Científicas (España)
DS Docta Complutense
RD 10 abr 2025