RT Journal Article T1 Development of a Method to Potentially Substitute Direct Evaluation of Mesopic Visual Acuity in Drivers A1 García Rojo, Marta María A1 Bonnin Arias, Cristina Natalia A1 Chamorro Gutiérrez, Eva A1 Álvarez Peregrina, Cristina A1 Sánchez Ramos, Celia AB (1) Background: In mesopic lighting conditions, or under adverse environmental circumstances, visual information is reduced, which increases the risk of traffic accidents. This effect could be reduced with a precise evaluation of the visual function under mesopic conditions, but it is difficult to replicate in clinics. This study aims to develop an easy-to-adopt method to evaluate mesopic visual acuity (VA) in drivers. (2) Methods: Prospective and observational study in drivers. logMAR mesopic VA was compared with photopic VA measured under different combinations of contrast charts and filters to find the combination that responds best to mesopic conditions. (3) Results: Fifty-six drivers were examined. The best correlation was found with an 80% density filter and a Weber contrast chart of 20%. The logMAR VA for this combination was 0.01 ± 0.11, which was close to the mesopic VA values (0.01 ± 0.12). The difference between both logMAR VA was 0.00 ± 0.06 (R = 0.86; p ≤ 0.001; ICC = 0.86). (4) Conclusions: The use of 20% contrast optotypes and the interposition of an 80% filter under photopic conditions provide VA values similar to those measured under mesopic lighting conditions, making this simple system a good predictor of mesopic VA values. PB MDPI SN 1660-4601 (e) YR 2021 FD 2021-04-29 LK https://hdl.handle.net/20.500.14352/8142 UL https://hdl.handle.net/20.500.14352/8142 LA eng NO Received: 2 March 2021. Accepted: 26 April 2021. Published: 29 April 2021.This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). DS Docta Complutense RD 7 abr 2025