RT Journal Article
T1 Tuning mesoporous silica dissolution in physiological environments: a review
A1 Paris, J.L.
A1 Colilla Nieto, Montserrat
A1 Izquierdo Barba, Isabel
A1 Manzano García, Miguel
A1 Vallet Regí, María Dulce Nombre
AB Matrix degradation has a major impact on the release kinetics of drug delivery systems. Regarding ordered mesoporous silica materials for biomedical applications, their dissolution is an important parameter that should be taken into  consideration. In this paper, we review the main factors that govern the mesoporous silica dissolution in physiological environments. We also provide the necessary knowledge to researchers in the area for tuning the dissolution rate of those matrices, so the degradation could be controlled and the material behaviour optimised.
PB Springer Verlag
SN 0022-2461
YR 2017
FD 2017
LK https://hdl.handle.net/20.500.14352/17663
UL https://hdl.handle.net/20.500.14352/17663
LA spa
NO RESEARCHER ID K-3719-2014 (Miguel Manzano García)ORCID 0000-0001-6238-6111 (Miguel Manzano García)RESEARCHER ID M-3378-2014 (María Vallet Regí)ORCID 0000-0002-6104-4889 (María Vallet Regí)
NO Unión Europea. H2020
NO Ministerio de Economía y Competitividad (MINECO)
NO Secretaría de Estado de Investigación, Desarrollo e Innovación
DS Docta Complutense
RD 23 jul 2024