RT Journal Article T1 Intestinal T-cell lymphoma in an Asian small-clawed otter: case report and literature review of lymphoma in the subfamily Lutrinae A1 Rebollada Merino, Agustín Miguel A1 Rocío Canales, A1 Umberto Romani-Cremaschi, A1 Rodríguez Bertos, Antonio Manuel AB The Asian small-clawed otter ( Aonyx cinereus) is an endangered species that is common in zoologic collections. A 17-y-old female Asian small-clawed otter under human care, with a clinical history of chronic renal disease, was euthanized because of deteriorating health. Histologically, the jejunal wall was infiltrated by a monomorphic population of small neoplastic lymphocytes that expanded the lamina propria of the villi and crypts, and on rare occasions invaded the submucosa. The tumor was composed of T cells (CD3+) with a proliferation index of 16%. Based on the World Health Organization (WHO) Classification of Hematopoietic Neoplasms in Domestic Animals, this lymphoma was classified as an enteropathy-associated T-cell lymphoma (EATL) type 2. We also present here a review of the literature on intestinal lymphoma in the subfamily Lutrinae (otters). SN 1040-6387 YR 2022 FD 2022-11-16 LK https://hdl.handle.net/20.500.14352/107580 UL https://hdl.handle.net/20.500.14352/107580 LA eng NO Rebollada A*, Canales R, Romani-Cremaschi U and Rodriguez-Bertos A. Intestinal T-cell lymphoma in an Asian small-clawed otter: case report and literature review of lymphoma in the subfamily Lutrinae. Journal of Veterinary Diagnostic Investigation , 35(1):72-75. 2023. (A). ISSN: 1040-6387. Impact factor: 1.200. Category: Veterinary Sciences, Quartile: 3, Position: 90 of 167. DOI: 10.1177/10406387221138293 NO Ministerio de Ciencia, Innovación y Universidades DS Docta Complutense RD 9 abr 2025