RT Journal Article
T1 Anaphylaxis to Oral Iron Salts. Desensitization Protocol for Tolerance Induction
A1 De Barrio, M
A1 Fuentes, V
A1 Tornero, P
A1 Sánchez, I
A1 Herrero, T
A1 Zubeldia Ortuño, José Manuel
AB Allergies to iron salts are seldom reported. We studied a patient with iron-deficiency anemia who had suffered anaphylactic reactions caused by oral iron salts. An allergy study was performed using single-blind, placebo-controlled oral challenge and skin tests with various iron salts as well as excipients in commercial formulations. Oral challenges were positive for 2 of the commercial formulations of iron salts. Intradermal tests with ferrous sulphate and ferrous lactate also showed positive results. All of the cutaneous tests using the excipients were negative. A desensitization protocol was designed which enabled us to readminister ferrous sulphate, although antihistamines were necessary to guarantee good tolerance to iron salts. We report a patient with allergy to iron salts, positive skin tests, and positive controlled challenge. We highlight the desensitization protocol designed to complete the therapeutic management of the anemia.
PB ESMON
YR 2008
FD 2008-01-08
LK https://hdl.handle.net/20.500.14352/115660
UL https://hdl.handle.net/20.500.14352/115660
LA eng
NO de Barrio M, Fuentes V, Tornero P, Sánchez I, Zubeldia J, Herrero T. Anaphylaxis to oral iron salts. desensitization protocol for tolerance induction. J Investig Allergol Clin Immunol. 2008;18(4):305-8. PMID: 18714540.
DS Docta Complutense
RD 17 abr 2025