RT Journal Article
T1 Microcirculation Improvement in Diabetic Foot Patients after Treatment with Sucrose Octasulfate-Impregnated Dressings
A1 Lázaro-Martínez, José Luis
A1 García-Madrid, Marta
A1 Bohbot, Serge
A1 López Moral, Mateo
A1 Álvaro Afonso, Francisco Javier
A1 García Álvarez, Yolanda
AB To assess the patients’ microcirculation evolution during the treatment with a sucrose octasulfate-impregnated dressing, fifty patients with neuroischaemic DFU treated with TLC-NOSF dressing were included in a prospective study between November 2020 and February 2022. TcpO2 values were measured on the dorsalis pedis or tibial posterior arteries’ angiosome according to the ulcer location. TcpO2 values were assessed at day 0 and every 4 weeks during 20 weeks of thefollow-up or until the wound healed. A cut-off point of tcpO2 < 30 mmHg was defined for patients with impaired microcirculation. The TcpO2 values showed an increase between day 0 and the end of the study, 33.04 � 12.27 mmHg and 40.89 � 13.06 mmHg, respectively, p < 0.001. Patients with impaired microcirculation showed an increase in the tcpO2 values from day 0 to the end of the study (p = 0.023). Furthermore, we observed a significant increase in the TcpO2 values in the forefoot DFU (p = 0.002) and in the rearfoot DFU (p = 0.071), with no difference between the ulcer locations (p = 0.694). The local treatment with TLC-NOSF dressing improved the microcirculation in patients with neuroischaemic DFU, regardless of microcirculation status at the baseline, and in the forefoot, regardless of the location.
PB MDPI
SN 2077-0383
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/73338
UL https://hdl.handle.net/20.500.14352/73338
LA eng
NO Laboratoires Urgo Medical
DS Docta Complutense
RD 3 may 2024