RT Journal Article
T1 Acute Impacts of Different Types of Exercise on Circulating α-Klotho Protein Levels
A1 Iturriaga, Tamara
A1 Yvert, Thomas
A1 Sanchez Lorente, Isabel M.
A1 Diez Vega, Ignacio
A1 Fernandez Elias, Valentin E.
A1 Sánchez Barroso, Lara
A1 Dominguez Balmaseda, Diego
A1 Larrosa Pérez, María Del Mar
A1 Pérez Ruiz, Margarita
A1 Santiago, Catalina
AB Introduction: Elevated plasma α-klotho (αKl) protects against several ageing phenotypes and has been proposed as a biomarker of a good prognosis for different diseases. The beneficial health effects of elevated plasma levels of soluble αKl (SαKl) have been likened to the positive effects of exercise on ageing and chronic disease progression. It has also been established that molecular responses and adaptations differ according to exercise dose. The aim of this study is to compare the acute SαKl response to different exercise interventions, cardiorespiratory, and strength exercise in healthy, physically active men and to examine the behavior of SαKl 72h after acute strength exercise.Methods: In this quasi-experimental study, plasma SαKl was measured before and after a cardiorespiratory exercise session (CR) in 43 men, and strength exercise session (ST) in 39 men. The behavior of SαKl was also examined 24, 48, and 72h after ST.Results: Significant differences (time×group) were detected in SαKl levels (p=0.001; d=0.86) between CR and ST. After the ST intervention, SαKl behavior varied significantly(p=0.009; d=0.663) in that levels dropped between pre- and post-exercises (p=0.025; d=0.756) and were also significantly higher compared to pre ST values at 24h (p=0.033;d=0.717) and at 48h (p=0.015; d=0.827).Conclusions: SαKl levels increased in response to a single bout of cardiorespiratory exercise; while they decreased immediately after strength exercise, levels were elevatedafter 24h indicating different klotho protein responses to different forms of exercise.
PB Frontiers
SN 1664-042X
YR 2021
FD 2021-09-01
LK https://hdl.handle.net/20.500.14352/94391
UL https://hdl.handle.net/20.500.14352/94391
LA eng
DS Docta Complutense
RD 9 abr 2025