RT Journal Article
T1 Corneal aberrations in primary congenital glaucoma and its visual correlation
A1 Ly-Yang, Fernando
A1 Morales Fernández, Laura
A1 García Bella, Javier
A1 Garcia Caride, Sara
A1 Santos Bueso, Enrique Miguel
A1 Saenz Frances, Federico
A1 Fernández-Vigo López, José
A1 García Feijoo, Julián
A1 Martínez De La Casa Fernández-Borrella, José María
AB Primary congenital glaucoma (PCG) can cause permanent vision loss, and its prognosis is related to early detection and treatment. The main pathological defect consists of resistance to aqueous outflow through the trabecular meshwork due to abnormal development of tissue derived from the neural crest in the anterior chamber angle. Even after successful intraocular pressure (IOP) management in PCG poor visual outcomes still present a lifelong challenge. Vision loss in PCG is multifactorial, resulting from optic nerve damage, corneal scarring, and myopic astigmatism associated with anisometropic amblyopia. Although it is already known that children with PCG present with an altered corneal configuration, the knowledge of irregular astigmatism due to high-order aberrations (HOA) and due to the unequal expansion of the anterior segment, and its impact on visual outcomes, is not yet fully understood, to the best of our knowledge.Quality vision is influenced by the presence of aberrations in the eye's optical system, which can degrade the quality of the image projected onto the retina. Low-order aberrations (LOA), including myopia, hyperopia, and regular astigmatism, can be corrected by spectacles, while HOA cannot be corrected by ordinary means. Coma and spherical aberrations are the most visually significant HOAs, while trefoil and other HOAs have a lower impact on visual quality.The purpose of this article is to establish a quantitative correlation between HOA and visual acuity (VA) to measure the magnitude of the impact of the altered cornea on visual outcomes in PCG.
PB Springer
YR 2024
FD 2024-04-29
LK https://hdl.handle.net/20.500.14352/104622
UL https://hdl.handle.net/20.500.14352/104622
LA eng
NO Ly-Yang F, Morales-Fernandez L, Garcia-Bella J, Garcia-Caride S, Santos-Bueso E, Saenz-Frances F, Fernandez-Vigo JI, Garcia-Feijoo J, Martinez-de-la-Casa JM. Corneal aberrations in primary congenital glaucoma and its visual correlation. Int Ophthalmol. 2024 Apr 29;44(1):209. doi: 10.1007/s10792-024-03150-5. PMID: 38683423.
NO Received: 16 August 2022; Accepted: 11 April 2024; Published: 29 April 2024
DS Docta Complutense
RD 29 jul 2025