RT Journal Article T1 Development of the Web-Based Spanish Version of the Barthel Index in Patients with Multiple Sclerosis A1 Aguilar-Zafra, Sandra A1 Del Corral Núñez Flores, Tamara A1 Valera Calero, Juan Antonio A1 Martín Casas, Patricia A1 Plaza Manzano, Gustavo A1 López de Uralde Villanueva, Ibai AB Background: The aims of this study were to develop a web-based Spanish form of the Barthel index (BI), to evaluate its psychometric properties and stability over time (test-retest), and to determine minimal detectable change (MDC) in patients with multiple sclerosis (MS). Methods: Participants answered the BI on two forms (web-based and face-to-face interview), 7–10 days apart. The internal consistency was evaluated using Cronbach’s alpha, and intraclass correlation (ICC) and kappa (κ) coefficients were used to investigate the agreement between both forms. Results: 143 participants were included. The Spanish web-based form of the BI showed excellent agreement between both forms for each item (κ = 0.86 (0.79 to 0.92), and for total score (κ = 0.87 (0.81 to 0.93); ICC = 0.99 (0.98 to 0.99). The internal consistency was good–excellent (Cronbach’s alpha = 0.89 (0.86–0.91)). The stability over time was adequate, the agreement of each item was κ = 0.63 (0.52–0.74)), and for total score (ICC = 0.97), determining a MDC95 of 12.09 points. Conclusions: The Spanish web-based form of the BI is a valid and reliable tool to assess functionality and can be applied in both formats in patients with MS. A total score difference of more than 12 points was found to indicate a deterioration or improvement in the patient’s functionality. PB MDPI SN 1660-4601 YR 2022 FD 2022-10-27 LK https://hdl.handle.net/20.500.14352/73421 UL https://hdl.handle.net/20.500.14352/73421 LA eng DS Docta Complutense RD 3 may 2024