RT Journal Article T1 Anterior Corneal Curvature and Aberration Changes After Scleral Lens Wear in Keratoconus Patients With and Without Ring Segments A1 Serramito Blanco, María A1 Carpena Torres, Carlos A1 Carballo Álvarez, Jesús A1 Piñero, David A1 Lipson, Michael A1 Carracedo Rodríguez, Juan Gonzalo AB Objective: To evaluate changes in the anterior corneal curvature and aberrometry after scleral contact lens wear in keratoconus (KC) subjects with and without intracorneal ring segments (ICRS).Methods: Twenty-six subjects diagnosed with keratoconus were selected to participate in the study. Subjects were divided into 2 groups, those with ICRS (KC-ICRS group) and those without ICRS (KC group). Subjects were instructed to wear 16.5-mm scleral lenses for 8 hours. Topographic and aberrometric parameters were evaluated before lens wear and immediately after lens removal. Anterior corneal curvature was evaluated at corneal diameters of 2, 4, 6, and 8 mm, and corneal aberrations were measured at 4-, 6-, and 8-mm pupil diameters.Results: The mean age of subjects was 36.95±8.95 years. In KC group, there was a statistically significant flattening of the central corneal curvature, from 6.98 to 7.09 mm (P<0.05). No changes were found in the central corneal curvature in the KC-ICRS group. The KC group showed anterior corneal curvature flattening, mainly in the nasal quadrant. The KC-ICRS group showed flattening primarily in the inferior hemisphere. In the KC group, spherical aberration for 6-mm pupil increased significantly. In the KC-ICRS group, changes in aberrations were significant for high-order root mean square at 4- and 6-mm pupil diameters (P<0.05), for oblique astigmatism for 4 mm and 6 mm, and for vertical coma for 4-mm pupil (P<0.05).Conclusion: Short-term scleral lens wear showed flattening of the anterior corneal surface in all subjects. In the KC group, the flattening was more pronounced in the nasal quadrant while changes were more pronounced inferiorly in KC-ICRS group. PB Wolters Kluwer SN 1542-2321 YR 2019 FD 2019 LK https://hdl.handle.net/20.500.14352/93230 UL https://hdl.handle.net/20.500.14352/93230 LA eng NO Serramito-Blanco, Maria M.Sc.; Carpena-Torres, Carlos M.Sc.; Carballo, Jesús Ph.D.; Piñero, David Ph.D.; Lipson, Michael O.D.; Carracedo, Gonzalo Ph.D.. Anterior Corneal Curvature and Aberration Changes After Scleral Lens Wear in Keratoconus Patients With and Without Ring Segments. Eye & Contact Lens: Science & Clinical Practice 45(2):p 141-148, March 2019. | DOI: 10.1097/ICL.0000000000000534 DS Docta Complutense RD 18 dic 2025