RT Journal Article
T1 Water-soluble BODIPY dyes: A novel approach for their sustainable chemistry and applied photonics
A1 Schad, Christopher
A1 Ray, Cesar
A1 Díaz Norambuena, Carolina
A1 Serrano Buitrago, Sergio
A1 Moreno Jiménez, Florencio
A1 Lora Maroto, Beatriz
A1 García Moreno, Inmaculada
A1 Muñoz Ubeda, Mónica
A1 Muñoz Úbeda, Mónica
A1 López Montero, Iván
A1 Bañuelos, Jorge
A1 Moya Cerero, Santiago de la
AB The BODIPY family of organic dyes has emerged as a cornerstone in photonics research development,driving innovation and advancement in various fields of high socio-economic interest. However, the majority of BODIPY dyes exhibit hydrophobic characteristics, resulting in poor solubility in water and other hydrophilic solvents. This solubility is paramount for their optimal utilization in a myriad of photonic applications, particularly in the realms of biology and medicine. Furthermore, it facilitates safer and more sustainable manipulation and chemical modification of these expansive dyes. Nevertheless, bestowing BODIPYs with water solubility while preserving their other essential properties, notably theirphotophysical signatures, poses a significant challenge. In this context, we present a straightforward general chemical modification aimed at converting conventional hydrophobic BODIPYs into highly hydrophilic variants, thus enabling their efficient solubilization in water and other hydrophilic solvents with minimal disruption to the dye's inherent photophysics. The efficacy of this methodology is demonstrated through the synthesis of a number of water-soluble BODIPY dyes featuring diverse substitution patterns. Furthermore, we showcase their utility in a spectrum of photonics-related applications, including in-water BODIPY chemistry and dye-laser technology, and fluorescence microscopy.
PB Royal Society of Chemistry
YR 2025
FD 2025-04-02
LK https://hdl.handle.net/20.500.14352/124132
UL https://hdl.handle.net/20.500.14352/124132
LA eng
NO Schad, Christopher, et al. «Water-Soluble BODIPY Dyes: A Novel Approach for Their Sustainable Chemistry and Applied Photonics». Chemical Science, vol. 16, n.o 18, 2025, pp. 8030-39. DOI.org (Crossref), https://doi.org/10.1039/D5SC01295C.
NO Ministerio de Ciencia e Innovación (España)
NO Gobierno Vasco
NO Universidad Complutense de Madrid
DS Docta Complutense
RD 18 dic 2025