RT Book, Section
T1 Functional Integrin Regulation Through Interactions with Tetraspanin CD9
A1 Torres Gómez, Álvaro
A1 Cardeñes, Beatriz
A1 Díez Sainz, Ester
A1 Lafuente Duarte, María Esther
A1 Cabañas Gutiérrez, Carlos
A2 Miguel Vicente-Manzanares, 
AB Integrins are adhesion receptors that mediate many intercellular and cell-extracellular matrix interactions with relevance in physiology and pathology. Unlike other cellular receptors, integrins critically require activation for ligand binding. Through interaction in cis with other molecules and the formation of tetraspanin-enriched membrane microdomains (TEMs), the tetraspanin CD9 regulates integrin activity and avidity. Here we present three techniques used to study CD9-integrin interactions and integrin activation.
PB Springer Nature Link
SN 9781071609613
SN 9781071609620
SN 1064-3745
SN 1940-6029
YR 2020
FD 2020-11-20
LK https://hdl.handle.net/20.500.14352/116124
UL https://hdl.handle.net/20.500.14352/116124
LA eng
NO Torres-Gómez, Á., Cardeñes, B., Díez-Sainz, E., Lafuente, E. M., & Cabañas, C. (2021). Functional Integrin Regulation Through Interactions with Tetraspanin CD9. Methods in molecular biology (Clifton, N.J.), 2217, 47–56. https://doi.org/10.1007/978-1-0716-0962-0_5
NO Ministerio Español de Economı́a y Competitividad (España)
DS Docta Complutense
RD 8 abr 2025