RT Journal Article
T1 Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia
A1 Úbeda D’Ocasar, Edurne
A1 Valera Calero, Juan Antonio
A1 Gallego Sendarrubias, Gracia María
A1 Fernández de las Peñas, César
A1 Arias Buría, José Luis
A1 Morales Cabezas, Matilde
A1 Arendt Nielsen, Lars
A1 Cigarán Méndez, Margarita
AB We aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia (FMS). One-hundred-and-twenty-six females with FMS completed demographic, pain-related variables, psychological, and sensitization outcomes as well as the S-LANSS and the PainDETECT questionnaires. S-LANSS was positively associated with BMI (r = 0.206), pain intensity (r = 0.206 to 0.298) and CSI score (r = 0.336) and negatively associated with all PPTs (r = −0.180 to −0.336). PainDETECT was negatively associated with age (r = −0.272) and all PPTs (r = −0.226 to −0.378) and positively correlated with pain intensity (r = 0.258 to 0.439), CSI (r = 0.538), anxiety (r = 0.246) and depression (r = 0.258). 51.4% of the S-LANSS was explained by PainDETECT (45.3%), posterior iliac PPT (0.2%) and mastoid PPT (5.9%), whereas the 56.4% of PainDETECT was explained by S-LANSS (43.4%), CSI (10.4%), and pain intensity (2.6%). This study found good convergent association between S-LANSS and PainDETECT in women with FMS. Additionally, S-LANSS was associated with PPTs whereas PainDETECT was associated with pain intensity and CSI, suggesting that both questionnaires assess different spectrums of the neuropathic and pain sensitization components of a condition and hence provide synergistic information.
PB Multidisciplinary Digital Publishing Institute (MDPI)
YR 2022
FD 2022-03-06
LK https://hdl.handle.net/20.500.14352/133696
UL https://hdl.handle.net/20.500.14352/133696
LA eng
NO Úbeda-D’ocasar E, Valera-Calero JA, Gallego-Sendarrubias GM, Fernández-De-las-peñas C, Arias-Buría JL, Morales-Cabezas M, et al. Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia. Biomedicines. 2022;10(3).
NO Esta investigación y los gastos de publicación (APC) fueron financiados por la Universidad Camilo José Cela, número de subvención MORQUACERMU
DS Docta Complutense
RD 21 mar 2026