RT Journal Article T1 Efficient treatment of breast cáncer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery A1 Kossatz, Susanne A1 Grandke, Julia A1 Couleaud, Pierre A1 Latorre, Alfonso A1 Aires, Antonio A1 Crosbie Staunton, Kieran A1 Ludwig, Robert A1 Dähring, Heidi A1 Ettelt, Volker A1 Lazaro Carrillo, Ana A1 Calero Calero, Macarena A1 Sader, Maha A1 Courty, José A1 Volkov, Yuri A1 Prina Mello, Adriele A1 Villanueva, Angeles A1 Somoza, Álvaro A1 Cortajarena, Aitziber A1 Miranda, Rodolfo A1 Hilger, Ingrid AB Tumor cells can effectively be killed by heat, e.g. by using magnetic hyperthermia. The main challenge in the field, however, is the generation of therapeutic temperatures selectively in the whole tumor region. We aimed to improve magnetic hyperthermia of breast cancer by using innovative nanoparticles which display a high heating potential and are functionalized with a cell internalization and a chemotherapeutic agent to increase cell death. YR 2015 FD 2015 LK https://hdl.handle.net/20.500.14352/92206 UL https://hdl.handle.net/20.500.14352/92206 LA eng NO Kossatz, S., Grandke, J., Couleaud, P. et al. Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery. Breast Cancer Res 17, 66 (2015). https://doi.org/10.1186/s13058-015-0576-1 NO European Commission DS Docta Complutense RD 14 dic 2025