TY  - JOUR
AU  - Morales, María Luz
AU  - García Vicente, Roberto
AU  - Rodrígue García, Alba
AU  - Reyes Palomares, Armando Adolfo
AU  - Vincelle Nieto, África
AU  - Álvarez, Noemí
AU  - Ortiz Ruiz, Alejandra
AU  - Garrido García, Vanesa
AU  - Giménez, Alicia
AU  - Carreño Tarragona, Gonzalo
AU  - Sánchez, Ricardo
AU  - Ayala Díaz, Rosa María
AU  - Martínez López, Joaquín
AU  - Linares Gómez, María
PY  - 2023
DO  - 10.1038/s41375-023-01963-4
SN  - 0887-6924
SN  - 1476-5551
UR  - https://hdl.handle.net/20.500.14352/101903
T2  - Leukemia
AB  - Despite the approval of several drugs for AML, cytarabine is still widely used as a therapeutic approach. However, 85% of patients show resistance and only 10% overcome the disease. Using RNA-seq and phosphoproteomics, we show that RNA splicing and...
LA  - eng
TI  - Posttranslational splicing modifications as a key mechanism in cytarabine resistance in acute myeloid leukemia
TY  - journal article
ER  -