RT Journal Article T1 Sucrose-Responsive Intercommunicated Janus Nanoparticles Network A1 Jimenez-Falcao, Sandra A1 Torres, Daniel A1 Martínez-Ruíz, Paloma A1 Vilela García, Diana A1 Martínez-Máñez, Ramón A1 Villalonga Santana, Reynaldo AB Inspired by biological systems, the development of artificial nanoscale materials that communicate over a short distance is still at its early stages. This work shows a new example of a cooperating system with intercommunicated devices at the nanoscale. The system is based on the new sucrose-responsive Janus gold-mesoporous silica (Janus Au-MS) nanoparticles network with two enzyme-powered nanodevices. These nanodevices involve two enzymatic processes based on invertase and glucose oxidase, which are anchored on the Au surfaces of different Janus Au-MS nanoparticles, and N-acetyl-L-cysteine and [Ru(bpy)3]2+ loaded as chemical messengers, respectively. Sucrose acts as the INPUT, triggering the sequential delivery of two different cargoes through the enzymatic control. Nanoscale communication using abiotic nanodevices is a developing potential research field and may prompt several applications in different disciplines, such as nanomedicine. PB MDPI SN 2079-4991 YR 2021 FD 2021 LK https://hdl.handle.net/20.500.14352/7466 UL https://hdl.handle.net/20.500.14352/7466 LA eng NO Ministerio de Economía y Competitividad NO MICINN NO Generalitat Valenciana DS Docta Complutense RD 8 abr 2025