RT Journal Article
T1 Efficacy of adjunctive anti‐plaque chemical agents in managing gingivitis: a systematic review and network meta‐analyses
A1 Figuero Ruiz, Elena
A1 Herrera González, David
A1 Tobías, Aurelio
A1 Serrano, Jorge
A1 Roldán, Silvia
A1 Escribano, Marta
A1 Martín Álvaro, María Concepción
AB AimThe aim of this network meta‐analysis (NMA) was to compare the efficacy of different oral hygiene products for chemical biofilm control, in 6‐month home‐use, randomized clinical trials (RCTs), in terms of changes in gingival index (GI).Material and MethodsSix‐month RCTs assessing GI were identified and screened for inclusion. Relevant information was extracted, and quality and potential risk of bias were estimated. Mean differences between baseline and end were calculated to obtain standardized mean differences (SMDs). NMA protocols were applied to assess direct and indirect comparisons among products using Löe & Silness GI, modified GI and gingival severity index.ResultsFifty‐three papers were included, 19 studies for mouth rinses, 32 for dentifrices, comprising data from 5,775 and 2,682 subjects, respectively. When ranking treatments, similar results were observed for all tested dentifrices, with the lowest effect observed for sanguinarine and baking soda. For mouth rinses, essential oils, triclosan–copolymer, chlorhexidine (at concentrations ≥ 0.10%) and cetylpyridinium chloride (>0.05%) demonstrated the greatest effect.ConclusionAlthough NMA revealed significant differences when comparing placebo versus some active agents, when comparing among active agents, no differences were found for dentifrices, while mouth rinses containing essential oils showed the greatest effect on GI scores.
PB Wiley
SN 0303-6979
YR 2019
FD 2019-05-31
LK https://hdl.handle.net/20.500.14352/115343
UL https://hdl.handle.net/20.500.14352/115343
LA eng
NO Figuero E, Herrera D, Tobías A, Serrano J, Roldán S, Escribano M, Martín C. Efficacy of adjunctive anti-plaque chemical agents in managing gingivitis: A systematic review and network meta-analyses. J Clin Periodontol. 2019 Jul;46(7):723-739. doi: 10.1111/jcpe.13127
DS Docta Complutense
RD 24 abr 2025