RT Journal Article T1 Pursuing precision in medicine and nutrition: the rise of electrochemical biosensing at the molecular level A1 Campuzano Ruiz, Susana A1 Barderas Manchado, Rodrigo A1 Moreno-Casbas, María Teresa A1 Almeida, Ángeles A1 Pingarrón Carrazón, José Manuel AB In the era that we seek personalization in material things, it is becoming increasingly clear that the individualized management of medicine and nutrition plays a key role in life expectancy and quality of life, allowing participation to some extent in our welfare and the use of societal resources in a rationale and equitable way. The implementation of precision medicine and nutrition are highly complex challenges which depend on the development of new technologies able to meet important requirements in terms of cost, simplicity, and versatility, and to determine both individually and simultaneously, almost in real time and with the required sensitivity and reliability, molecular markers of different omics levels in biofluids extracted, secreted (either naturally or stimulated), or circulating in the body. Relying on representative and pioneering examples, this review article critically discusses recent advances driving the position of electrochemical bioplatforms as one of the winning horses for the implementation of suitable tools for advanced diagnostics, therapy, and precision nutrition. In addition to a critical overview of the state of the art, including groundbreaking applications and challenges ahead, the article concludes with a personal vision of the imminent roadmap. PB Springer Nature SN 1618-2642 YR 2024 FD 2024 LK https://hdl.handle.net/20.500.14352/105232 UL https://hdl.handle.net/20.500.14352/105232 LA eng NO Campuzano, S., Barderas, R., Moreno-Casbas, M.T. et al. Pursuing precision in medicine and nutrition: the rise of electrochemical biosensing at the molecular level. Anal Bioanal Chem 416, 2151–2172 (2024). https://doi.org/10.1007/s00216-023-04805-5 NO Ministerio de Ciencia e Innovación DS Docta Complutense RD 4 abr 2025