RT Journal Article
T1 Beneficial Effects of the RESMENA Dietary Pattern on Oxidative Stress in Patients Suffering from Metabolic Syndrome with Hyperglycemia Are Associated to Dietary TAC and Fruit Consumption
A1 De La Iglesia, Rocio
A1 Lopez Legarrea, Patricia
A1 Celada, Paloma
A1 Sánchez Muniz, Francisco José
A1 Martínez, J. Alfredo
A1 Zulet, María Ángeles
AB Hyperglycemia and oxidative stress are conditions directly related to the metabolic syndrome (MetS), whose prevalence is increasing worldwide. This study aimed to evaluate the effectiveness of a new weight-loss dietary pattern on improving the oxidative stress status on patients suffering MetS with hyperglycemia. Seventy-nine volunteers were randomly assigned to two low-calorie diets (−30% Energy): the control diet based on the American Health Association criteria and the RESMENA diet based on a different macronutrient distribution (30% proteins, 30% lipids, 40% carbohydrates), which was characterized by an increase of the meal frequency (seven-times/day), low glycemic load, high antioxidant capacity (TAC) and high n-3 fatty acids content. Dietary records, anthropometrical measurements, biochemical parameters and oxidative stress biomarkers were analyzed before and after the six-month-long study. The RESMENA (Metabolic Syndrome Reduction in Navarra) diet specifically reduced the android fat mass and demonstrated more effectiveness on improving general oxidative stress through a greater decrease of oxidized LDL (oxLDL) values and protection against arylesterase depletion. Interestingly, oxLDL values were associated with dietary TAC and fruit consumption and with changes on body mass index (BMI), waist circumference, fat mass and triacilglyceride (TG) levels. In conclusion, the antioxidant properties of the RESMENA diet provide further benefits to those attributable to weight loss on patients suffering Mets with hyperglycemia.
PB MDPI
SN 1422-0067
YR 2013
FD 2013-03-27
LK https://hdl.handle.net/20.500.14352/34368
UL https://hdl.handle.net/20.500.14352/34368
LA eng
NO De La Iglesia, R.; Lopez-Legarrea, P.; Celada, P.; Sánchez-Muniz, F.; Martinez, J.; Zulet, M. Beneficial Effects of the RESMENA Dietary Pattern on Oxidative Stress in Patients Suffering from Metabolic Syndrome with Hyperglycemia Are Associated to Dietary TAC and Fruit Consumption. IJMS 2013, 14, 6903–6919, doi:10.3390/ijms14046903.
NO Consejería de Salud del Gobierno de Navarra
NO Universidad de Navarra
NO Instituto de Salud Carlos III (España)
DS Docta Complutense
RD 10 abr 2025